Vanadium Complex with Cinnulin PF® has been formulated to help support healthy blood sugar and lipid levels and support the pancreas. Vanadium Complex with Cinnulin PF® utilizes a number of nutrients to provide this support:‡
Cinnulin PF® is an appropriate nutritional support product for healthy glucose levels, body composition, blood pressure and antioxidant function in healthy individuals.‡
Cinnulin PF® is a proprietary water soluble extract of Cinnamomum burmannii. The proprietary extraction process helps filter out toxins found in whole cinnamon. It is the only extract standardized for doubly linked Type-A Polymers, specifically tetramers and trimers shown in clinical research to have a host of health benefits, particularly those related to Metabolic Syndrome. In a recent study, (Ziegenfuss, et al 2007) 83% of those given the active Type A Polymers experienced a significant decrease in fasting blood sugar (about an 8% drop), compared to only 33% in the placebo group. Moreover, subjects additionally showed statistically lower body fat, enhanced lean body mass, lower systolic blood pressure and saw improvements in various antioxidant measures.‡
Gymnema sylvestre is a woody vine that grows in tropical areas and has been used in Ayurvedic medicine. The Hindi name for gymnema means “Destroyer of Sugar”. Compounds found in gymnema have been found to decrease the absorption of sugar in the intestines. Several preliminary human trials indicate that Gymnema sylvestre supports pancreatic health by supporting beta cell function.‡
Vanadium is a mineral derived from bis-glycinato oxo vanadium, an organic combination of glycine and vanadium that promotes healthy glucose metabolism.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Ingredients
Dosage
Three vegetable capsules twice daily.
Count
90 Vegetable Capsules
Science
Ścibior A, Pietrzyk Ł, Plewa Z, Skiba A. Vanadium: Risks and possible benefits in the light of a comprehensive overview of its pharmacotoxicological mechanisms and multi-applications with a summary of further research trends. J Trace Elem Med Biol. 2020 Sep;61:126508. doi: 10.1016/j.jtemb.2020.126508. Epub 2020 Apr 12. PMID: 32305626; PMCID: PMC7152879.
Jacques-Camarena O, González-Ortiz M, Martínez-Abundis E, López-Madrueño JF, Medina-Santillán R. Effect of vanadium on insulin sensitivity in patients with impaired glucose tolerance. Ann Nutr Metab. 2008;53(3-4):195-8. doi: 10.1159/000175844. Epub 2008 Nov 22. PMID: 19033682.
Cohen N, Halberstam M, Shlimovich P, Chang CJ, Shamoon H, Rossetti L. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest. 1995 Jun;95(6):2501-9. doi: 10.1172/JCI117951. PMID: 7769096; PMCID: PMC295932.
Goldfine AB, Patti ME, Zuberi L, Goldstein BJ, LeBlanc R, Landaker EJ, Jiang ZY, Willsky GR, Kahn CR. Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies. Metabolism. 2000 Mar;49(3):400-10. doi: 10.1016/s0026-0495(00)90418-9. PMID: 10726921.
Cusi K, Cukier S, DeFronzo RA, Torres M, Puchulu FM, Redondo JC. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab. 2001 Mar;86(3):1410-7. doi: 10.1210/jcem.86.3.7337. PMID: 11238540.
Halberstam M, Cohen N, Shlimovich P, Rossetti L, Shamoon H. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes. 1996 May;45(5):659-66. doi: 10.2337/diab.45.5.659. Erratum in: Diabetes 1996 Sep;45(9):1285. PMID: 8621019.
Ziegenfuss TN, Hofheins JE, Mendel RW, Landis J, Anderson RA. Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr. 2006 Dec 28;3(2):45-53. doi: 10.1186/1550-2783-3-2-45. PMID: 18500972; PMCID: PMC2129164.
Rafehi H, Ververis K, Balcerczyk A, Ziemann M, Ooi J, Hu S, Kwa FA, Loveridge SJ, Georgiadis GT, El-Osta A, Karagiannis TC. Investigation of the biological properties of Cinnulin PF in the context of diabetes: mechanistic insights by genome-wide mRNA-Seq analysis. Pathobiol Aging Age Relat Dis. 2012;2. doi: 10.3402/pba.v2i0.11905. Epub 2012 Feb 22. PMID: 22953038; PMCID: PMC3417697.
Features :
Hygienic Product : Not Specified
Allergy : Not Specified
Vanadium Complex with Cinnulin PF® - 489C
Description
Vanadium Complex with Cinnulin PF® has been formulated to help support healthy blood sugar and lipid levels and support the pancreas. Vanadium Complex with Cinnulin PF® utilizes a number of nutrients to provide this support:‡
Cinnulin PF® is an appropriate nutritional support product for healthy glucose levels, body composition, blood pressure and antioxidant function in healthy individuals.‡
Cinnulin PF® is a proprietary water soluble extract of Cinnamomum burmannii. The proprietary extraction process helps filter out toxins found in whole cinnamon. It is the only extract standardized for doubly linked Type-A Polymers, specifically tetramers and trimers shown in clinical research to have a host of health benefits, particularly those related to Metabolic Syndrome. In a recent study, (Ziegenfuss, et al 2007) 83% of those given the active Type A Polymers experienced a significant decrease in fasting blood sugar (about an 8% drop), compared to only 33% in the placebo group. Moreover, subjects additionally showed statistically lower body fat, enhanced lean body mass, lower systolic blood pressure and saw improvements in various antioxidant measures.‡
Gymnema sylvestre is a woody vine that grows in tropical areas and has been used in Ayurvedic medicine. The Hindi name for gymnema means “Destroyer of Sugar”. Compounds found in gymnema have been found to decrease the absorption of sugar in the intestines. Several preliminary human trials indicate that Gymnema sylvestre supports pancreatic health by supporting beta cell function.‡
Vanadium is a mineral derived from bis-glycinato oxo vanadium, an organic combination of glycine and vanadium that promotes healthy glucose metabolism.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Ingredients
Dosage
Three vegetable capsules twice daily.
Count
90 Vegetable Capsules
Science
Ścibior A, Pietrzyk Ł, Plewa Z, Skiba A. Vanadium: Risks and possible benefits in the light of a comprehensive overview of its pharmacotoxicological mechanisms and multi-applications with a summary of further research trends. J Trace Elem Med Biol. 2020 Sep;61:126508. doi: 10.1016/j.jtemb.2020.126508. Epub 2020 Apr 12. PMID: 32305626; PMCID: PMC7152879.
Jacques-Camarena O, González-Ortiz M, Martínez-Abundis E, López-Madrueño JF, Medina-Santillán R. Effect of vanadium on insulin sensitivity in patients with impaired glucose tolerance. Ann Nutr Metab. 2008;53(3-4):195-8. doi: 10.1159/000175844. Epub 2008 Nov 22. PMID: 19033682.
Cohen N, Halberstam M, Shlimovich P, Chang CJ, Shamoon H, Rossetti L. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest. 1995 Jun;95(6):2501-9. doi: 10.1172/JCI117951. PMID: 7769096; PMCID: PMC295932.
Goldfine AB, Patti ME, Zuberi L, Goldstein BJ, LeBlanc R, Landaker EJ, Jiang ZY, Willsky GR, Kahn CR. Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies. Metabolism. 2000 Mar;49(3):400-10. doi: 10.1016/s0026-0495(00)90418-9. PMID: 10726921.
Cusi K, Cukier S, DeFronzo RA, Torres M, Puchulu FM, Redondo JC. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab. 2001 Mar;86(3):1410-7. doi: 10.1210/jcem.86.3.7337. PMID: 11238540.
Halberstam M, Cohen N, Shlimovich P, Rossetti L, Shamoon H. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes. 1996 May;45(5):659-66. doi: 10.2337/diab.45.5.659. Erratum in: Diabetes 1996 Sep;45(9):1285. PMID: 8621019.
Ziegenfuss TN, Hofheins JE, Mendel RW, Landis J, Anderson RA. Effects of a water-soluble cinnamon extract on body composition and features of the metabolic syndrome in pre-diabetic men and women. J Int Soc Sports Nutr. 2006 Dec 28;3(2):45-53. doi: 10.1186/1550-2783-3-2-45. PMID: 18500972; PMCID: PMC2129164.
Rafehi H, Ververis K, Balcerczyk A, Ziemann M, Ooi J, Hu S, Kwa FA, Loveridge SJ, Georgiadis GT, El-Osta A, Karagiannis TC. Investigation of the biological properties of Cinnulin PF in the context of diabetes: mechanistic insights by genome-wide mRNA-Seq analysis. Pathobiol Aging Age Relat Dis. 2012;2. doi: 10.3402/pba.v2i0.11905. Epub 2012 Feb 22. PMID: 22953038; PMCID: PMC3417697.
