GABA

SKU: 459

Title: 90 Capsules
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Description

Gamma-aminobutyric acid (GABA) is a neurotransmitter, or chemical messenger, in the brain.   It is a natural calming and anti-epileptic agent made in the brain that is manufactured from glutamine and glucose.  The brain contains many neurotransmitters that trigger or inhibit specific reactions in the body.  GABA calms the nervous system by preventing the transmission of certain signals. ‡

GABA is the primary inhibitory neurotransmitter in the central nervous system and participates in cell-to-cell communication.  Healthy GABA levels have been associated with positive mood.  A recent study indicates that GABA also enhances alpha wave production in the brain to promote relaxation and moderate occasional stress.  In the same study, it supported healthy IgA levels, suggesting that it may support immune health during occasional stress.‡

Too much excitation can lead to irritability, restlessness, sleeplessness, and spasmodic movements which requires balancing.  GABA, as an inhibitory neurotransmitter, can provide this balance.  Studies also indicate GABA can promote relaxation and enhance sleep.  Research indicates that low GABA levels or decreased GABA function in the brain may have an adverse impact on neurological health.‡

 

 

Warning:  If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.

‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.

Ingredients

Dosage

One capsule daily.

Count

90 Capsules

Science

Allen MJ, Sabir S, Sharma S. GABA Receptor. [Updated 2023 Feb 13]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK526124/

Ngo, D.-H.; Vo, T.S. An Updated Review on Pharmaceutical Properties of Gamma-Aminobutyric Acid. Molecules 2019, 24, 2678. https://doi.org/10.3390/molecules24152678

Steenbergen, L., Sellaro, R., Stock, AK. et al. RETRACTED ARTICLE: γ-Aminobutyric acid (GABA) administration improves action selection processes: a randomised controlled trial. Sci Rep 5, 12770 (2015). https://doi.org/10.1038/srep12770

Yoto, A., Murao, S., Motoki, M. et al. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks. Amino Acids 43, 1331–1337 (2012). https://doi.org/10.1007/s00726-011-1206-6

Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. PMID: 26500584; PMCID: PMC4594160.

Todd N, Zhang Y, Power C, Becerra L, Borsook D, Livingstone M, McDannold N. Modulation of brain function by targeted delivery of GABA through the disrupted blood-brain barrier. Neuroimage. 2019 Apr 1;189:267-275. doi: 10.1016/j.neuroimage.2019.01.037. Epub 2019 Jan 16. PMID: 30659957; PMCID: PMC6422703.

Hepsomali P, Groeger JA, Nishihira J, Scholey A. Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review. Front Neurosci. 2020 Sep 17;14:923. doi: 10.3389/fnins.2020.00923. PMID: 33041752; PMCID: PMC7527439.

Hepsomali P, Groeger JA, Nishihira J, Scholey A. Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review. Front Neurosci. 2020 Sep 17;14:923. doi: 10.3389/fnins.2020.00923. PMID: 33041752; PMCID: PMC7527439.

Briguglio M, Dell’Osso B, Panzica G, Malgaroli A, Banfi G, Zanaboni Dina C, Galentino R, Porta M. Dietary Neurotransmitters: A Narrative Review on Current Knowledge. Nutrients. 2018 May 10;10(5):591. doi: 10.3390/nu10050591. PMID: 29748506; PMCID: PMC5986471.

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