Folate 400 90's - FOL49
- Supports methylation, which maintains healthy neurotransmission, DNA synthesis and gene regulation1
- Provides all of the benefits of folic acid regardless of MTHFR genetic variations2‡
- Supports cardiovascular, cellular and neuronal health‡
- Available in 400 mcg and 1, 000 mcg
- Offers Metafolin® L-5-MTHF, a naturally occurring, universally metabolized form of folate
- Made with high-quality ingredients backed by verifiable science
Indications
- Ages 18 and up
- Universally metabolized form of folate‡
Suggested Use
Folate 400
As a dietary supplement, take 1 capsule, 1-2 times daily, with meals.
Folate 1, 000
As a dietary supplement, take 1 capsule daily, with a meal.
Verifiable Science
This formula has Metafolin® L-5-methyltetrahydrofolate (L-5-MTHF), a naturally occurring, universally metabolized form of folate. Unlike folic acid, L-5-MTHF does not require activation by DHFR (dihydrofolate reductase) and MTHFR (methylene tetrahydrofolate reductase), enzymes thatare subject to functional and genetic variations that may reduce conversion efficiency.2-4‡
References
- Gropper SS, Smith JL, Groff JL. Advanced Nutrition and Human Metabolism. 5th ed. Belmont, CA: Wadsworth; 2009.
- Prinz-Langenohl R, et al. Br J Pharmacol. 2009 Dec; 158(8): 2014-21.
- Seremak-Mrozikiewicz A. Ginekol Pol.2013 Jul;84(7):641-6.
- Patanwala I, et al. Am J Clin Nutr. 2014 Aug;100(2):593-9.
