Paradex® - 433

Description

Paradex® is a botanical formulation designed to support a healthy balance of intestinal microorganisms, support a healthy digestion, and support against internal parasites.‡

Black walnut hull is beneficial as an antimicrobial.  Animal studies show benefit for wormwood as an anti-parasitic and supports healthy digestion.  Pau d’arco is a dietary supplement made from the inner bark of several species of Tabebuia trees that grow in Central and South America and some studies have shown possible benefit in treatment of infections.‡

Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.

‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.

Ingredients

Dosage

One capsule daily.

Count

90 Capsules

Science

Wenzel J, Storer Samaniego C, Wang L, Burrows L, Tucker E, Dwarshuis N, Ammerman M, Zand A. Antioxidant potential of Juglans nigra, black walnut, husks extracted using supercritical carbon dioxide with an ethanol modifier. Food Sci Nutr. 2016 May 20;5(2):223-232. doi: 10.1002/fsn3.385. PMID: 28265357; PMCID: PMC5332255.

Serrano J, Puupponen-Pimiä R, Dauer A, Aura AM, Saura-Calixto F. Tannins: current knowledge of food sources, intake, bioavailability and biological effects. Mol Nutr Food Res. 2009 Sep;53 Suppl 2:S310-29. doi: 10.1002/mnfr.200900039. PMID: 19437486.

Cheraghali F, Shojaee-Aliabadi S, Hosseini SM, Mirmoghtadaie L, Mortazavian AM, Ghanati K, Abedi AS, Moslemi M. Characterization of Microcapsule Containing Walnut (Juglans regia L.) Green Husk Extract as Preventive Antioxidant and Antimicrobial Agent. Int J Prev Med. 2018 Nov 15;9:101. doi: 10.4103/ijpvm.IJPVM_308_18. PMID: 30598739; PMCID: PMC6259432.

Fischer TC, Gosch C, Mirbeth B, Gselmann M, Thallmair V, Stich K. Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora. J Agric Food Chem. 2012 Dec 12;60(49):12074-81. doi: 10.1021/jf303584r. Epub 2012 Nov 29. PMID: 23163769.

Beshay EVN. Therapeutic efficacy of Artemisia absinthium against Hymenolepis nana: in vitro and in vivo studies in comparison with the anthelmintic praziquantel. J Helminthol. 2018 May;92(3):298-308. doi: 10.1017/S0022149X17000529. Epub 2017 Jun 13. PMID: 28606189.

Waller PJ, Bernes G, Thamsborg SM, Sukura A, Richter SH, Ingebrigtsen K, Höglund J. Plants as de-worming agents of livestock in the Nordic countries: historical perspective, popular beliefs and prospects for the future. Acta Vet Scand. 2001;42(1):31-44. doi: 10.1186/1751-0147-42-31. PMID: 11455900; PMCID: PMC2202332.

Richter M, Winkel AF, Schummer D, Gerlitz M, de Hoop M, Brunner B, Glien M, Schmoll D. Pau d’arco activates Nrf2-dependent gene expression via the MEK/ERK-pathway. J Toxicol Sci. 2014 Apr;39(2):353-61. doi: 10.2131/jts.39.353. PMID: 24646717.

Pereira EM, Machado Tde B, Leal IC, Jesus DM, Damaso CR, Pinto AV, Giambiagi-deMarval M, Kuster RM, Santos KR. Tabebuia avellanedae naphthoquinones: activity against methicillin-resistant staphylococcal strains, cytotoxic activity and in vivo dermal irritability analysis. Ann Clin Microbiol Antimicrob. 2006 Mar 22;5:5. doi: 10.1186/1476-0711-5-5. PMID: 16553949; PMCID: PMC1435768.

Chen K, Xie K, Liu Z, Nakasone Y, Sakao K, Hossain A, Hou DX. Preventive Effects and Mechanisms of Garlic on Dyslipidemia and Gut Microbiome Dysbiosis. Nutrients. 2019 May 29;11(6):1225. doi: 10.3390/nu11061225. PMID: 31146458; PMCID: PMC6627858.

Krstin S, Sobeh M, Braun MS, Wink M. Anti-Parasitic Activities of Allium sativum and Allium cepa against Trypanosoma b. brucei and Leishmania tarentolae. Medicines (Basel). 2018 Apr 21;5(2):37. doi: 10.3390/medicines5020037. PMID: 29690511; PMCID: PMC6023319.

Features :

• Hygienic Product : Not Specified
• Allergy : Not Specified