Melatonin 20mg
SKU:
M-20
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Description

Higher potency melatonin is not intended to be used to support sleep.  Instead Melatonin 20mg support supports cellular health, immune health, and antioxidant activity. Melatonin helps provide cellular support for tissues including the colon, breast, prostate and lungs.

Synthesis of melatonin from the amino acid tryptophan can be decreased by the aging process.  Melatonin is a potent antioxidant.  Adequate melatonin levels have been reported to be a positive factor for cardiovascular, neuroendocrine, and bone health.‡

 

 

Warning:  If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.

‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.

Ingredients

SKU – 3720

 

SKU – 3721

Dosage

One vegetable capsule daily.

Count

SKU – 60 Vegetable Capsules

SKU – 180 Vegetable Capsules

Science

Auger RR, Burgess HJ, Emens JS, Deriy LV, Thomas SM, Sharkey KM. Clinical Practice Guideline for the Treatment of Intrinsic Circadian Rhythm Sleep-Wake Disorders: Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD), and Irregular Sleep-Wake Rhythm Disorder (ISWRD). An Update for 2015: An American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med. 2015 Oct 15;11(10):1199-236. doi: 10.5664/jcsm.5100. PMID: 26414986; PMCID: PMC4582061.

Auld F, Maschauer EL, Morrison I, Skene DJ, Riha RL. Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders. Sleep Med Rev. 2017 Aug;34:10-22. doi: 10.1016/j.smrv.2016.06.005. Epub 2016 Jul 20. PMID: 28648359.

Costello RB, Lentino CV, Boyd CC, O’Connell ML, Crawford CC, Sprengel ML, Deuster PA. The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature. Nutr J. 2014 Nov 7;13:106. doi: 10.1186/1475-2891-13-106. PMID: 25380732; PMCID: PMC4273450.

Hansen MV, Halladin NL, Rosenberg J, Gögenur I, Møller AM. Melatonin for pre- and postoperative anxiety in adults. Cochrane Database Syst Rev. 2015 Apr 9;2015(4):CD009861. doi: 10.1002/14651858.CD009861.pub2. Update in: Cochrane Database Syst Rev. 2020 Dec 8;12:CD009861. PMID: 25856551; PMCID: PMC6464333.

McDonagh MS, Holmes R, Hsu F. Pharmacologic Treatments for Sleep Disorders in Children: A Systematic Review. J Child Neurol. 2019 Apr;34(5):237-247. doi: 10.1177/0883073818821030. Epub 2019 Jan 23. PMID: 30674203.

Qaseem A, Kansagara D, Forciea MA, Cooke M, Denberg TD; Clinical Guidelines Committee of the American College of Physicians. Management of Chronic Insomnia Disorder in Adults: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. 2016 Jul 19;165(2):125-33. doi: 10.7326/M15-2175. Epub 2016 May 3. PMID: 27136449.

Malhotra S, Sawhney G, Pandhi P. The therapeutic potential of melatonin: a review of the science. MedGenMed. 2004 Apr 13;6(2):46. PMID: 15266271; PMCID: PMC1395802.

Weishaupt JH, Bartels C, Polking E, et al. Reduced oxidative damage in ALS by high-dose enteral melatonin treatment. J Pineal Res. 2006 Nov;41(4):313-23.

Ceyran H, Narin F, Narin N, et al. The effect of high dose melatonin on cardiac ischemia- reperfusion Injury. Yonsei Med J. 2008 Oct 31;49(5):735-41.

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