B-12 and folic acid regulate the formation of red blood cells. B-12 is also required for proper digestion and absorption, protein synthesis and metabolism of carbohydrates and fats.‡
Includes folic acid in the bioavailable form of methyl folate for the growth and reproduction of red and white blood cells, the conversion of homocysteine to methionine, and the production of gastric hydrochloric acid.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Ingredients
Dosage
One tablet daily.
Chew or dissolve in mouth before swallowing, or swallow whole.
Count
60 Tablets
Science
Nalder L, Zheng B, Chiandet G, Middleton LT, de Jager CA. Vitamin B12 and Folate Status in Cognitively Healthy Older Adults and Associations with Cognitive Performance. J Nutr Health Aging. 2021;25(3):287-294. doi: 10.1007/s12603-020-1489-y. PMID: 33575718.
Issac TG, Soundarya S, Christopher R, Chandra SR. Vitamin B12 deficiency: an important reversible co-morbidity in neuropsychiatric manifestations. Indian J Psychol Med. 2015 Jan-Mar;37(1):26-9. doi: 10.4103/0253-7176.150809. PMID: 25722508; PMCID: PMC4341306.
Gröber U, Kisters K, Schmidt J. Neuroenhancement with vitamin B12-underestimated neurological significance. Nutrients. 2013 Dec 12;5(12):5031-45. doi: 10.3390/nu5125031. PMID: 24352086; PMCID: PMC3875920.
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Vitamin B. [Updated 2021 May 27]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK548710/
Wolffenbuttel BHR, Wouters HJCM, Heiner-Fokkema MR, van der Klauw MM. The Many Faces of Cobalamin (Vitamin B12) Deficiency. Mayo Clin Proc Innov Qual Outcomes. 2019 May 27;3(2):200-214. doi: 10.1016/j.mayocpiqo.2019.03.002. PMID: 31193945; PMCID: PMC6543499.
Chrysant SG, Chrysant GS. The current status of homocysteine as a risk factor for cardiovascular disease: a mini review. Expert Rev Cardiovasc Ther. 2018 Aug;16(8):559-565. doi: 10.1080/14779072.2018.1497974. Epub 2018 Jul 17. PMID: 29979619.
DiBaise M, Tarleton SM. Hair, Nails, and Skin: Differentiating Cutaneous Manifestations of Micronutrient Deficiency. Nutr Clin Pract. 2019 Aug;34(4):490-503. doi: 10.1002/ncp.10321. Epub 2019 May 29. PMID: 31144371.
Koury MJ, Ponka P. New insights into erythropoiesis: the roles of folate, vitamin B12, and iron. Annu Rev Nutr. 2004;24:105-31. doi: 10.1146/annurev.nutr.24.012003.132306. PMID: 15189115.
BACON F. CHOW, PH.D., HOWARD H. STONE, M.D., The Relationship of Vitamin B12 to Carbohydrate Metabolism and Diabetes Mellitus, The American Journal of Clinical Nutrition, Volume 5, Issue 4, July-August 1957, Pages 431–439, https://doi.org/10.1093/ajcn/5.4.431
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Hygienic Product : Not Specified
Allergy : Not Specified
Description
B-12 and folic acid regulate the formation of red blood cells. B-12 is also required for proper digestion and absorption, protein synthesis and metabolism of carbohydrates and fats.‡
Includes folic acid in the bioavailable form of methyl folate for the growth and reproduction of red and white blood cells, the conversion of homocysteine to methionine, and the production of gastric hydrochloric acid.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Ingredients
Dosage
One tablet daily.
Chew or dissolve in mouth before swallowing, or swallow whole.
Count
60 Tablets
Science
Nalder L, Zheng B, Chiandet G, Middleton LT, de Jager CA. Vitamin B12 and Folate Status in Cognitively Healthy Older Adults and Associations with Cognitive Performance. J Nutr Health Aging. 2021;25(3):287-294. doi: 10.1007/s12603-020-1489-y. PMID: 33575718.
Issac TG, Soundarya S, Christopher R, Chandra SR. Vitamin B12 deficiency: an important reversible co-morbidity in neuropsychiatric manifestations. Indian J Psychol Med. 2015 Jan-Mar;37(1):26-9. doi: 10.4103/0253-7176.150809. PMID: 25722508; PMCID: PMC4341306.
Gröber U, Kisters K, Schmidt J. Neuroenhancement with vitamin B12-underestimated neurological significance. Nutrients. 2013 Dec 12;5(12):5031-45. doi: 10.3390/nu5125031. PMID: 24352086; PMCID: PMC3875920.
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Vitamin B. [Updated 2021 May 27]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK548710/
Wolffenbuttel BHR, Wouters HJCM, Heiner-Fokkema MR, van der Klauw MM. The Many Faces of Cobalamin (Vitamin B12) Deficiency. Mayo Clin Proc Innov Qual Outcomes. 2019 May 27;3(2):200-214. doi: 10.1016/j.mayocpiqo.2019.03.002. PMID: 31193945; PMCID: PMC6543499.
Chrysant SG, Chrysant GS. The current status of homocysteine as a risk factor for cardiovascular disease: a mini review. Expert Rev Cardiovasc Ther. 2018 Aug;16(8):559-565. doi: 10.1080/14779072.2018.1497974. Epub 2018 Jul 17. PMID: 29979619.
DiBaise M, Tarleton SM. Hair, Nails, and Skin: Differentiating Cutaneous Manifestations of Micronutrient Deficiency. Nutr Clin Pract. 2019 Aug;34(4):490-503. doi: 10.1002/ncp.10321. Epub 2019 May 29. PMID: 31144371.
Koury MJ, Ponka P. New insights into erythropoiesis: the roles of folate, vitamin B12, and iron. Annu Rev Nutr. 2004;24:105-31. doi: 10.1146/annurev.nutr.24.012003.132306. PMID: 15189115.
BACON F. CHOW, PH.D., HOWARD H. STONE, M.D., The Relationship of Vitamin B12 to Carbohydrate Metabolism and Diabetes Mellitus, The American Journal of Clinical Nutrition, Volume 5, Issue 4, July-August 1957, Pages 431–439, https://doi.org/10.1093/ajcn/5.4.431
