Alpha Lipoic Acid – also known as lipoic acid, thiotic acid or ALA – is a water and fat soluble compound found in every cell in the body and helps convert glucose to energy by assisting in the digestion and conversion of carbohydrates to fuel. As a result of improving glucose and fat metabolism, ALA can be beneficial regarding healthy weight management. Additionally, ALA can help support healthy triglyceride levels and blood glucose levels.‡
ALA is a potent antioxidant often referred to as the “universal antioxidant”. As an antioxidant, ALA can help slow down cellular damage that occurs due to exposure to free radicals, and helps to restore levels of essential vitamins such as vitamin E and vitamin C. The antioxidant attributes of Alpha Lipoic Acid decrease the oxidative damage created by exercise-induced oxidative stress, and can support in muscle regeneration after exercise, especially when taken with creatine.‡
Alpha Lipoic Acid has been studied in Europe for beneficial effects related to neuropathic symptoms such as numbness, prickling, stabbing and burning pain, etc. that can be associated with certain neural-related situations.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Ingredients
Dosage
One or two capsules daily.
Count
60 Capsules
Science
Nguyen H, Gupta V. Alpha-Lipoic Acid. [Updated 2022 Sep 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK564301/
Packer L, Cadenas E. Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling. J Clin Biochem Nutr. 2011 Jan;48(1):26-32. doi: 10.3164/jcbn.11-005FR. Epub 2010 Dec 29. PMID: 21297908; PMCID: PMC3022059.
Golbidi S, Badran M, Laher I. Diabetes and alpha lipoic Acid. Front Pharmacol. 2011 Nov 17;2:69. doi: 10.3389/fphar.2011.00069. PMID: 22125537; PMCID: PMC3221300.
Anna Gorąca, Halina Huk-Kolega, Aleksandra Piechota, Paulina Kleniewska, Elżbieta Ciejka, Beata Skibska, Lipoic acid – biological activity and therapeutic potential, Pharmacological Reports, Volume 63, Issue 4, 2011, Pages 849-858, ISSN 1734-1140, https://doi.org/10.1016/S1734-1140(11)70600-4.
Kola B. Role of AMP-activated protein kinase in the control of appetite. J Neuroendocrinol. 2008 Jul;20(7):942-51. doi: 10.1111/j.1365-2826.2008.01745.x. Epub 2008 Apr 28. PMID: 18445126; PMCID: PMC2658714.
Kim MS, Park JY, Namkoong C, Jang PG, Ryu JW, Song HS, Yun JY, Namgoong IS, Ha J, Park IS, Lee IK, Viollet B, Youn JH, Lee HK, Lee KU. Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. Nat Med. 2004 Jul;10(7):727-33. doi: 10.1038/nm1061. Epub 2004 Jun 13. PMID: 15195087.
Namazi N, Larijani B, Azadbakht L. Alpha-lipoic acid supplement in obesity treatment: A systematic review and meta-analysis of clinical trials. Clin Nutr. 2018 Apr;37(2):419-428. doi: 10.1016/j.clnu.2017.06.002. Epub 2017 Jun 8. PMID: 28629898.
Streeper RS, Henriksen EJ, Jacob S, Hokama JY, Fogt DL, Tritschler HJ. Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle. Am J Physiol. 1997 Jul;273(1 Pt 1):E185-91. doi: 10.1152/ajpendo.1997.273.1.E185. PMID: 9252495.
Jacob S, Streeper RS, Fogt DL, Hokama JY, Tritschler HJ, Dietze GJ, Henriksen EJ. The antioxidant alpha-lipoic acid enhances insulin-stimulated glucose metabolism in insulin-resistant rat skeletal muscle. Diabetes. 1996 Aug;45(8):1024-9. doi: 10.2337/diab.45.8.1024. PMID: 8690147.
Foster TS. Efficacy and safety of alpha-lipoic acid supplementation in the treatment of symptomatic diabetic neuropathy. Diabetes Educ. 2007 Jan-Feb;33(1):111-7. doi: 10.1177/0145721706297450. PMID: 17272797.
Gorąca A, Huk-Kolega H, Piechota A, Kleniewska P, Ciejka E, Skibska B. Lipoic acid – biological activity and therapeutic potential. Pharmacol Rep. 2011;63(4):849-58. doi: 10.1016/s1734-1140(11)70600-4. PMID: 22001972.
Sola S, Mir MQ, Cheema FA, Khan-Merchant N, Menon RG, Parthasarathy S, Khan BV. Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome: results of the Irbesartan and Lipoic Acid in Endothelial Dysfunction (ISLAND) study. Circulation. 2005 Jan 25;111(3):343-8. doi: 10.1161/01.CIR.0000153272.48711.B9. Epub 2005 Jan 17. PMID: 15655130.
Hashimoto Y, Yoshizawa K, Kaido Y, Takenouchi A, Terao K, Yasui H, Yoshikawa Y. Exercise Performance Upregulatory Effect of R-α-Lipoic Acid with γ-Cyclodextrin. Nutrients. 2021 Dec 22;14(1):21. doi: 10.3390/nu14010021. PMID: 35010896; PMCID: PMC8746793.
Features :
Hygienic Product : Not Specified
Allergy : Not Specified
Description
Alpha Lipoic Acid – also known as lipoic acid, thiotic acid or ALA – is a water and fat soluble compound found in every cell in the body and helps convert glucose to energy by assisting in the digestion and conversion of carbohydrates to fuel. As a result of improving glucose and fat metabolism, ALA can be beneficial regarding healthy weight management. Additionally, ALA can help support healthy triglyceride levels and blood glucose levels.‡
ALA is a potent antioxidant often referred to as the “universal antioxidant”. As an antioxidant, ALA can help slow down cellular damage that occurs due to exposure to free radicals, and helps to restore levels of essential vitamins such as vitamin E and vitamin C. The antioxidant attributes of Alpha Lipoic Acid decrease the oxidative damage created by exercise-induced oxidative stress, and can support in muscle regeneration after exercise, especially when taken with creatine.‡
Alpha Lipoic Acid has been studied in Europe for beneficial effects related to neuropathic symptoms such as numbness, prickling, stabbing and burning pain, etc. that can be associated with certain neural-related situations.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Ingredients
Dosage
One or two capsules daily.
Count
60 Capsules
Science
Nguyen H, Gupta V. Alpha-Lipoic Acid. [Updated 2022 Sep 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK564301/
Packer L, Cadenas E. Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling. J Clin Biochem Nutr. 2011 Jan;48(1):26-32. doi: 10.3164/jcbn.11-005FR. Epub 2010 Dec 29. PMID: 21297908; PMCID: PMC3022059.
Golbidi S, Badran M, Laher I. Diabetes and alpha lipoic Acid. Front Pharmacol. 2011 Nov 17;2:69. doi: 10.3389/fphar.2011.00069. PMID: 22125537; PMCID: PMC3221300.
Anna Gorąca, Halina Huk-Kolega, Aleksandra Piechota, Paulina Kleniewska, Elżbieta Ciejka, Beata Skibska, Lipoic acid – biological activity and therapeutic potential, Pharmacological Reports, Volume 63, Issue 4, 2011, Pages 849-858, ISSN 1734-1140, https://doi.org/10.1016/S1734-1140(11)70600-4.
Kola B. Role of AMP-activated protein kinase in the control of appetite. J Neuroendocrinol. 2008 Jul;20(7):942-51. doi: 10.1111/j.1365-2826.2008.01745.x. Epub 2008 Apr 28. PMID: 18445126; PMCID: PMC2658714.
Kim MS, Park JY, Namkoong C, Jang PG, Ryu JW, Song HS, Yun JY, Namgoong IS, Ha J, Park IS, Lee IK, Viollet B, Youn JH, Lee HK, Lee KU. Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. Nat Med. 2004 Jul;10(7):727-33. doi: 10.1038/nm1061. Epub 2004 Jun 13. PMID: 15195087.
Namazi N, Larijani B, Azadbakht L. Alpha-lipoic acid supplement in obesity treatment: A systematic review and meta-analysis of clinical trials. Clin Nutr. 2018 Apr;37(2):419-428. doi: 10.1016/j.clnu.2017.06.002. Epub 2017 Jun 8. PMID: 28629898.
Streeper RS, Henriksen EJ, Jacob S, Hokama JY, Fogt DL, Tritschler HJ. Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle. Am J Physiol. 1997 Jul;273(1 Pt 1):E185-91. doi: 10.1152/ajpendo.1997.273.1.E185. PMID: 9252495.
Jacob S, Streeper RS, Fogt DL, Hokama JY, Tritschler HJ, Dietze GJ, Henriksen EJ. The antioxidant alpha-lipoic acid enhances insulin-stimulated glucose metabolism in insulin-resistant rat skeletal muscle. Diabetes. 1996 Aug;45(8):1024-9. doi: 10.2337/diab.45.8.1024. PMID: 8690147.
Foster TS. Efficacy and safety of alpha-lipoic acid supplementation in the treatment of symptomatic diabetic neuropathy. Diabetes Educ. 2007 Jan-Feb;33(1):111-7. doi: 10.1177/0145721706297450. PMID: 17272797.
Gorąca A, Huk-Kolega H, Piechota A, Kleniewska P, Ciejka E, Skibska B. Lipoic acid – biological activity and therapeutic potential. Pharmacol Rep. 2011;63(4):849-58. doi: 10.1016/s1734-1140(11)70600-4. PMID: 22001972.
Sola S, Mir MQ, Cheema FA, Khan-Merchant N, Menon RG, Parthasarathy S, Khan BV. Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome: results of the Irbesartan and Lipoic Acid in Endothelial Dysfunction (ISLAND) study. Circulation. 2005 Jan 25;111(3):343-8. doi: 10.1161/01.CIR.0000153272.48711.B9. Epub 2005 Jan 17. PMID: 15655130.
Hashimoto Y, Yoshizawa K, Kaido Y, Takenouchi A, Terao K, Yasui H, Yoshikawa Y. Exercise Performance Upregulatory Effect of R-α-Lipoic Acid with γ-Cyclodextrin. Nutrients. 2021 Dec 22;14(1):21. doi: 10.3390/nu14010021. PMID: 35010896; PMCID: PMC8746793.
