Methyl Folate supplies 5 mg (5,000 mcg) of biologically active folate called Metafolin (6S) 5-methyltetrahydrofolate (5-MTHF). 5-MTHF is the predominant form of folate commonly found in cells and is essential for overall health, as it participates as a cofactor in a reaction that involves the remethylation of homocysteine to methionine. 5-MTHF is directly usable by the body and has been shown to be the only form of folate to cross the blood-brain barrier.‡
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