Magnesium is a mineral that is abundant in the body, andis a cofactor in more than 300 enzyme systems. These enzyme systems regulate many diverse reactions within the body including protein synthesis, muscle and nerve function, blood glucose control and blood pressure regulation.‡
Magnesium is required for energy production and supports the structural development of bone and is required for the synthesis of DNA, RNA and glutathione. Magnesium also plays a role in processes important to nerve conduction, muscle contractions and normal heart rhythm.‡
Magnesium deficiency is not uncommon in the United States, and is particularly common among African Americans. The overall prevalence of magnesium deficiency in African Americans (predominantly female) was 20% based on a study of urban African Americans. Magnesium deficiency has also been noted in people with a history of alcoholism (6 times more likely), in people with chronic diarrhea, and 2/3 of people in intensive
care.‡
Magnesium Complex combines three powerful, “energetic” forms of magnesium – citrate, aspartate and malate – each molecule chelated to substrates of the Krebs cycle or to other energy-producing components found in healthy foods:‡
Citric Acid, found in tomatoes, oranges, lemons, and limes, is important as an intermediate in the citric acid or Krebs cycle, which is core to healthy human metabolism.‡
Aspartic Acid occurs in many vegetables including sprouting seeds and avocados, and is a critical component of energy production at the cellular level.‡
Malic Acid is formed in metabolic cycles in the cells of plants and is partly responsible for the stimulating, refreshing experience of biting into a juicy apple or cherry. Malic acid provides cells with energy via the Krebs cycle and provides building blocks for the formation of amino acids.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Ingredients
Dosage
Take four vegetable capsules daily, with food.
Count
120 Vegetable Capsules
Science
Veronese N, Dominguez LJ, Pizzol D, Demurtas J, Smith L, Barbagallo M. Oral Magnesium Supplementation for Treating Glucose Metabolism Parameters in People with or at Risk of Diabetes: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials. Nutrients. 2021 Nov 15;13(11):4074. doi: 10.3390/nu13114074. PMID: 34836329; PMCID: PMC8619199.
de Baaij JH, Hoenderop JG, Bindels RJ. Magnesium in man: implications for health and disease. Physiol Rev. 2015 Jan;95(1):1-46. doi: 10.1152/physrev.00012.2014. PMID: 25540137.
Pickering G, Mazur A, Trousselard M, Bienkowski P, Yaltsewa N, Amessou M, Noah L, Pouteau E. Magnesium Status and Stress: The Vicious Circle Concept Revisited. Nutrients. 2020 Nov 28;12(12):3672. doi: 10.3390/nu12123672. PMID: 33260549; PMCID: PMC7761127.
Tarleton EK, Littenberg B, MacLean CD, Kennedy AG, Daley C. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial. PLoS One. 2017 Jun 27;12(6):e0180067. doi: 10.1371/journal.pone.0180067. PMID: 28654669; PMCID: PMC5487054.
Dibaba DT, Xun P, Song Y, Rosanoff A, Shechter M, He K. The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2017 Sep;106(3):921-929. doi: 10.3945/ajcn.117.155291. Epub 2017 Jul 19. PMID: 28724644; PMCID: PMC5573024.
Rosanoff A, Costello RB, Johnson GH. Effectively Prescribing Oral Magnesium Therapy for Hypertension: A Categorized Systematic Review of 49 Clinical Trials. Nutrients. 2021 Jan 10;13(1):195. doi: 10.3390/nu13010195. PMID: 33435187; PMCID: PMC7827637.
DiNicolantonio JJ, O’Keefe JH, Wilson W. Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis. Open Heart. 2018 Jan 13;5(1):e000668. doi: 10.1136/openhrt-2017-000668. Erratum in: Open Heart. 2018 Apr 5;5(1):e000668corr1. PMID: 29387426; PMCID: PMC5786912.
National Institutes of Health. Magnesium.
Zhang Y, Xun P, Wang R, Mao L, He K. Can Magnesium Enhance Exercise Performance? Nutrients. 2017 Aug 28;9(9):946. doi: 10.3390/nu9090946. PMID: 28846654; PMCID: PMC5622706.
Barbagallo M, Dominguez LJ. Magnesium and type 2 diabetes. World J Diabetes. 2015 Aug 25;6(10):1152-7. doi: 10.4239/wjd.v6.i10.1152. PMID: 26322160; PMCID: PMC4549665.
Zhang X, Li Y, Del Gobbo LC, Rosanoff A, Wang J, Zhang W, Song Y. Effects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trials. Hypertension. 2016 Aug;68(2):324-33. doi: 10.1161/HYPERTENSIONAHA.116.07664. Epub 2016 Jul 11. PMID: 27402922.
Features :
Hygienic Product : Not Specified
Allergy : Not Specified
Magnesium Complex - 1038
Description
Magnesium is a mineral that is abundant in the body, andis a cofactor in more than 300 enzyme systems. These enzyme systems regulate many diverse reactions within the body including protein synthesis, muscle and nerve function, blood glucose control and blood pressure regulation.‡
Magnesium is required for energy production and supports the structural development of bone and is required for the synthesis of DNA, RNA and glutathione. Magnesium also plays a role in processes important to nerve conduction, muscle contractions and normal heart rhythm.‡
Magnesium deficiency is not uncommon in the United States, and is particularly common among African Americans. The overall prevalence of magnesium deficiency in African Americans (predominantly female) was 20% based on a study of urban African Americans. Magnesium deficiency has also been noted in people with a history of alcoholism (6 times more likely), in people with chronic diarrhea, and 2/3 of people in intensive
care.‡
Magnesium Complex combines three powerful, “energetic” forms of magnesium – citrate, aspartate and malate – each molecule chelated to substrates of the Krebs cycle or to other energy-producing components found in healthy foods:‡
Citric Acid, found in tomatoes, oranges, lemons, and limes, is important as an intermediate in the citric acid or Krebs cycle, which is core to healthy human metabolism.‡
Aspartic Acid occurs in many vegetables including sprouting seeds and avocados, and is a critical component of energy production at the cellular level.‡
Malic Acid is formed in metabolic cycles in the cells of plants and is partly responsible for the stimulating, refreshing experience of biting into a juicy apple or cherry. Malic acid provides cells with energy via the Krebs cycle and provides building blocks for the formation of amino acids.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Ingredients
Dosage
Take four vegetable capsules daily, with food.
Count
120 Vegetable Capsules
Science
Veronese N, Dominguez LJ, Pizzol D, Demurtas J, Smith L, Barbagallo M. Oral Magnesium Supplementation for Treating Glucose Metabolism Parameters in People with or at Risk of Diabetes: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials. Nutrients. 2021 Nov 15;13(11):4074. doi: 10.3390/nu13114074. PMID: 34836329; PMCID: PMC8619199.
de Baaij JH, Hoenderop JG, Bindels RJ. Magnesium in man: implications for health and disease. Physiol Rev. 2015 Jan;95(1):1-46. doi: 10.1152/physrev.00012.2014. PMID: 25540137.
Pickering G, Mazur A, Trousselard M, Bienkowski P, Yaltsewa N, Amessou M, Noah L, Pouteau E. Magnesium Status and Stress: The Vicious Circle Concept Revisited. Nutrients. 2020 Nov 28;12(12):3672. doi: 10.3390/nu12123672. PMID: 33260549; PMCID: PMC7761127.
Tarleton EK, Littenberg B, MacLean CD, Kennedy AG, Daley C. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial. PLoS One. 2017 Jun 27;12(6):e0180067. doi: 10.1371/journal.pone.0180067. PMID: 28654669; PMCID: PMC5487054.
Dibaba DT, Xun P, Song Y, Rosanoff A, Shechter M, He K. The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2017 Sep;106(3):921-929. doi: 10.3945/ajcn.117.155291. Epub 2017 Jul 19. PMID: 28724644; PMCID: PMC5573024.
Rosanoff A, Costello RB, Johnson GH. Effectively Prescribing Oral Magnesium Therapy for Hypertension: A Categorized Systematic Review of 49 Clinical Trials. Nutrients. 2021 Jan 10;13(1):195. doi: 10.3390/nu13010195. PMID: 33435187; PMCID: PMC7827637.
DiNicolantonio JJ, O’Keefe JH, Wilson W. Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis. Open Heart. 2018 Jan 13;5(1):e000668. doi: 10.1136/openhrt-2017-000668. Erratum in: Open Heart. 2018 Apr 5;5(1):e000668corr1. PMID: 29387426; PMCID: PMC5786912.
National Institutes of Health. Magnesium.
Zhang Y, Xun P, Wang R, Mao L, He K. Can Magnesium Enhance Exercise Performance? Nutrients. 2017 Aug 28;9(9):946. doi: 10.3390/nu9090946. PMID: 28846654; PMCID: PMC5622706.
Barbagallo M, Dominguez LJ. Magnesium and type 2 diabetes. World J Diabetes. 2015 Aug 25;6(10):1152-7. doi: 10.4239/wjd.v6.i10.1152. PMID: 26322160; PMCID: PMC4549665.
Zhang X, Li Y, Del Gobbo LC, Rosanoff A, Wang J, Zhang W, Song Y. Effects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trials. Hypertension. 2016 Aug;68(2):324-33. doi: 10.1161/HYPERTENSIONAHA.116.07664. Epub 2016 Jul 11. PMID: 27402922.
