Vitamin A + Carotenoids 90's - VA59
- Provides preformed vitamin A, which bypasses genetic variations that limit conversion of beta-carotene‡
- Supports optical lens health and macular pigment density‡
- Provides antioxidant defenses to protect retinal health‡
- Part of the PureGenomics® product line
- Made with high-quality ingredients backed by verifiable science
Indications
- Ages 18 and up
- Eye health‡
- Immune function support‡
Suggested Use
As a dietary supplement, take 1 capsule daily, with a meal.
Verifiable Science
The ability to convert provitamin A carotenoids, like beta carotene, into active vitamin A varies from one person to the next, owing to genetic variations that can limit enzyme activity. Single nucleotide polymorphisms (SNPs) in the gene encoding the enzyme BCMO1 (β-Carotene 15, 15'-monooxygenase 1) can decrease the conversion efficacy of carotenoids into retinal, the immediate precursor of vitamin A, by up to 69%.1 These common variations can be bypassed with dietary retinol (vitamin A).2 Since variations in the BCMO1 gene have also been associated with macular pigment density, this formula includes a blend of lutein, zeaxanthin and astaxanthin to promote macular health.3 Lutein and zeaxanthin are the two carotenoids found in macular pigment; as such, they act to support the integrity and density of the pigment, as well as optical lens health.4 Astaxanthin offers support for antioxidant defenses to protect retinal health.5‡
References
- Lietz G, et al. J Nutr.2012 Jan;142(1):161S-5S.
- Leung WC, et al. FASEB J.2009 Apr;23(4):1041-53.
- Feigl B, et al. PLoS One. 2014 Feb 19;9(2):e89069.
- Age-Related Eye Disease Study 2 (AREDS2) Research Group, Chew EY, Clemons TE, et al. JAMA Ophthalmol. 2014 Feb;132(2):142-9.
- Piermarocchi S, et al. Eur J Ophthalmol. 2012 Mar-Apr;22(2):216-25.
