Vital Immunity® - 412

Description

Vital Immunity® uses several clinically-studied ingredients to support the immune system and Phase 2 detoxification‡:

• BroccoRaphanin™ is supported by clinical data that shows it helps the body’s natural detoxification process and immune protection by supporting the body’s natural defenses.  This activated form of BroccoRaphanin™ contains stabilized myrosinase, an enzyme important for the optimal conversion of the active ingredients.‡
• Milk Thistle extract provides silymarin which supports liver function. Silymarin also provides antioxidant protection and stimulates protein synthesis on a cellular level.  The liver is an important organ in detoxifying blood and supporting a healthy immune system.^‡
• Indole-3-carbinol (I3C) has been shown to promote healthy phase I cytochrome P450 detoxification enzymes and phase II detoxification enzymes such as glutathione
  S-transferase, which supports the liver’s ability to process and eliminate harmful compounds.  I3C is also believed to contribute to healthy cellular support.‡
• Diindolylmethane, or DIM, is a component of  indole-3-carbinol, and is found in vegetables of the brassica family such as broccoli, kale, and cauliflower.‡

Warning:  If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.

‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.

Ingredients

Dosage

One vegetable capsule daily.

Count

30 Vegetable Capsules

Science

Xu L, Nagata N, Ota T. Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance. Adipocyte. 2018;7(3):218-225. doi: 10.1080/21623945.2018.1474669. Epub 2018 Aug 9. PMID: 29898626; PMCID: PMC6261473.

Clinical and molecular evidence of the consumption of broccoli, glucoraphanin and sulforaphane in humans January 2015Nutricion hospitalaria: organo oficial de la Sociedad Espanola de Nutricion Parenteral y Enteral 31(2):559-569 DOI:10.3305/nh.2015.31.2.7685

Thomas W. Kensler, Derek Ng, Steven G. Carmella, Menglan Chen, Lisa P. Jacobson, Alvaro Muñoz, Patricia A. Egner, Jian Guo Chen, Geng Sun Qian, Tao Yang Chen, Jed W. Fahey, Paul Talalay, John D. Groopman, Jian-Min Yuan, Stephen S. Hecht, Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China, Carcinogenesis, Volume 33, Issue 1, January 2012, Pages 101–107, https://doi.org/10.1093/carcin/bgr229

Mahn A, Castillo A. Potential of Sulforaphane as a Natural Immune System Enhancer: A Review. Molecules. 2021 Feb 1;26(3):752. doi: 10.3390/molecules26030752. PMID: 33535560; PMCID: PMC7867070.

Li Z, Guo H, Li J, Ma T, Zhou S, Zhang Z, Miao L, Cai L. Sulforaphane prevents type 2 diabetes-induced nephropathy via AMPK-mediated activation of lipid metabolic pathways and Nrf2 antioxidative function. Clin Sci (Lond). 2020 Sep 30;134(18):2469-2487. doi: 10.1042/CS20191088. PMID: 32940670.

Sedlak TW, Nucifora LG, Koga M, Shaffer LS, Higgs C, Tanaka T, Wang AM, Coughlin JM, Barker PB, Fahey JW, Sawa A. Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects: A Clinical Pilot Study. Mol Neuropsychiatry. 2018 May;3(4):214-222. doi: 10.1159/000487639. Epub 2018 Apr 17. PMID: 29888232; PMCID: PMC5981770.

Abenavoli L, Izzo AA, Milić N, Cicala C, Santini A, Capasso R. Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases. Phytother Res. 2018 Nov;32(11):2202-2213. doi: 10.1002/ptr.6171. Epub 2018 Aug 6. PMID: 30080294.

Camini FC, Costa DC. Silymarin: not just another antioxidant. J Basic Clin Physiol Pharmacol. 2020 Mar 5;31(4):/j/jbcpp.2020.31.issue-4/jbcpp-2019-0206/jbcpp-2019-0206.xml. doi: 10.1515/jbcpp-2019-0206. PMID: 32134732.

de Avelar CR, Pereira EM, de Farias Costa PR, de Jesus RP, de Oliveira LPM. Effect of silymarin on biochemical indicators in patients with liver disease: Systematic review with meta-analysis. World J Gastroenterol. 2017 Jul 21;23(27):5004-5017. doi: 10.3748/wjg.v23.i27.5004. PMID: 28785154; PMCID: PMC5526770.

Tajmohammadi A, Razavi BM, Hosseinzadeh H. Silybum marianum (milk thistle) and its main constituent, silymarin, as a potential therapeutic plant in metabolic syndrome: A review. Phytother Res. 2018 Oct;32(10):1933-1949. doi: 10.1002/ptr.6153. Epub 2018 Jul 17. PMID: 30015401.

Aller R, Izaola O, Gómez S, Tafur C, González G, Berroa E, Mora N, González JM, de Luis DA. Effect of silymarin plus vitamin E in patients with non-alcoholic fatty liver disease. A randomized clinical pilot study. Eur Rev Med Pharmacol Sci. 2015 Aug;19(16):3118-24. PMID: 26367736.

Vargas-Mendoza N, Madrigal-Santillán E, Morales-González A, Esquivel-Soto J, Esquivel-Chirino C, García-Luna Y González-Rubio M, Gayosso-de-Lucio JA, Morales-González JA. Hepatoprotective effect of silymarin. World J Hepatol. 2014 Mar 27;6(3):144-9. doi: 10.4254/wjh.v6.i3.144. PMID: 24672644; PMCID: PMC3959115.

Features :

• Hygienic Product : Not Specified
• Allergy : Not Specified