Acetyl-L-Carnitine, the acetylated form of L-carnitine, is an amino acid (a building block for proteins) that is naturally produced in the body. Both L-carnitine and acetyl-L-carnitine have similar energy and metabolism promoting properties.‡
Acetyl-L-Carnitine is found naturally in the body and supports the availability of acetyl-CoA, an important energy generating metabolite. Additionally, it supports proper mitochondrial function and cell membrane stability. The acetyl group that is part of Acetyl-L-Carnitine contributes to the production of the neurotransmitter acetylcholine, which is required for mental function.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Ingredients
Dosage
One capsule twice daily
Count
60 capsules
Science
Pennisi M, Lanza G, Cantone M, D’Amico E, Fisicaro F, Puglisi V, Vinciguerra L, Bella R, Vicari E, Malaguarnera G. Acetyl-L-Carnitine in Dementia and Other Cognitive Disorders: A Critical Update. Nutrients. 2020 May 12;12(5):1389. doi: 10.3390/nu12051389. PMID: 32408706; PMCID: PMC7284336.
Chen N, Yang M, Zhou M, Xiao J, Guo J, He L. L-carnitine for cognitive enhancement in people without cognitive impairment. Cochrane Database Syst Rev. 2017 Mar 26;3(3):CD009374. doi: 10.1002/14651858.CD009374.pub3. PMID: 28349514; PMCID: PMC6464592.
WesnesKeith A, Josh R. The Effects on the Cognitive Function of Healthy Volunteers of a Combination of Acetyl-L-Carnitine, Vinpocetine and Huperzine A Administered Over 28 Days. Int J Neurol Neurother. 2019;6(2). doi:10.23937/2378-3001/1410089
Hudson S, Tabet N. Acetyl-L-carnitine for dementia. Cochrane Database Syst Rev. 2003;2003(2):CD003158. doi: 10.1002/14651858.CD003158. PMID: 12804452; PMCID: PMC6991156.
Jones LL, McDonald DA, Borum PR. Acylcarnitines: role in brain. Prog Lipid Res. 2010 Jan;49(1):61-75. doi: 10.1016/j.plipres.2009.08.004. Epub 2009 Aug 29. PMID: 19720082.
Malaguarnera M, Gargante MP, Cristaldi E, Colonna V, Messano M, Koverech A, Neri S, Vacante M, Cammalleri L, Motta M. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue. Arch Gerontol Geriatr. 2008 Mar-Apr;46(2):181-90. doi: 10.1016/j.archger.2007.03.012. Epub 2007 Jul 20. PMID: 17658628.
Cristofano A, Sapere N, La Marca G, Angiolillo A, Vitale M, Corbi G, Scapagnini G, Intrieri M, Russo C, Corso G, Di Costanzo A. Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer’s Dementia. PLoS One. 2016 May 19;11(5):e0155694. doi: 10.1371/journal.pone.0155694. PMID: 27196316; PMCID: PMC4873244.
Cristofano A, Sapere N, La Marca G, Angiolillo A, Vitale M, Corbi G, Scapagnini G, Intrieri M, Russo C, Corso G, Di Costanzo A. Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer’s Dementia. PLoS One. 2016 May 19;11(5):e0155694. doi: 10.1371/journal.pone.0155694. PMID: 27196316; PMCID: PMC4873244.
Barnes CA, Markowska AL, Ingram DK, Kametani H, Spangler EL, Lemken VJ, Olton DS. Acetyl-1-carnitine. 2: Effects on learning and memory performance of aged rats in simple and complex mazes. Neurobiol Aging. 1990 Sep-Oct;11(5):499-506. doi: 10.1016/0197-4580(90)90110-l. PMID: 2234280.
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Description
Acetyl-L-Carnitine, the acetylated form of L-carnitine, is an amino acid (a building block for proteins) that is naturally produced in the body. Both L-carnitine and acetyl-L-carnitine have similar energy and metabolism promoting properties.‡
Acetyl-L-Carnitine is found naturally in the body and supports the availability of acetyl-CoA, an important energy generating metabolite. Additionally, it supports proper mitochondrial function and cell membrane stability. The acetyl group that is part of Acetyl-L-Carnitine contributes to the production of the neurotransmitter acetylcholine, which is required for mental function.‡
Warning: If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.
‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.
Ingredients
Dosage
One capsule twice daily
Count
60 capsules
Science
Pennisi M, Lanza G, Cantone M, D’Amico E, Fisicaro F, Puglisi V, Vinciguerra L, Bella R, Vicari E, Malaguarnera G. Acetyl-L-Carnitine in Dementia and Other Cognitive Disorders: A Critical Update. Nutrients. 2020 May 12;12(5):1389. doi: 10.3390/nu12051389. PMID: 32408706; PMCID: PMC7284336.
Chen N, Yang M, Zhou M, Xiao J, Guo J, He L. L-carnitine for cognitive enhancement in people without cognitive impairment. Cochrane Database Syst Rev. 2017 Mar 26;3(3):CD009374. doi: 10.1002/14651858.CD009374.pub3. PMID: 28349514; PMCID: PMC6464592.
WesnesKeith A, Josh R. The Effects on the Cognitive Function of Healthy Volunteers of a Combination of Acetyl-L-Carnitine, Vinpocetine and Huperzine A Administered Over 28 Days. Int J Neurol Neurother. 2019;6(2). doi:10.23937/2378-3001/1410089
Hudson S, Tabet N. Acetyl-L-carnitine for dementia. Cochrane Database Syst Rev. 2003;2003(2):CD003158. doi: 10.1002/14651858.CD003158. PMID: 12804452; PMCID: PMC6991156.
Jones LL, McDonald DA, Borum PR. Acylcarnitines: role in brain. Prog Lipid Res. 2010 Jan;49(1):61-75. doi: 10.1016/j.plipres.2009.08.004. Epub 2009 Aug 29. PMID: 19720082.
Malaguarnera M, Gargante MP, Cristaldi E, Colonna V, Messano M, Koverech A, Neri S, Vacante M, Cammalleri L, Motta M. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue. Arch Gerontol Geriatr. 2008 Mar-Apr;46(2):181-90. doi: 10.1016/j.archger.2007.03.012. Epub 2007 Jul 20. PMID: 17658628.
Cristofano A, Sapere N, La Marca G, Angiolillo A, Vitale M, Corbi G, Scapagnini G, Intrieri M, Russo C, Corso G, Di Costanzo A. Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer’s Dementia. PLoS One. 2016 May 19;11(5):e0155694. doi: 10.1371/journal.pone.0155694. PMID: 27196316; PMCID: PMC4873244.
Cristofano A, Sapere N, La Marca G, Angiolillo A, Vitale M, Corbi G, Scapagnini G, Intrieri M, Russo C, Corso G, Di Costanzo A. Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer’s Dementia. PLoS One. 2016 May 19;11(5):e0155694. doi: 10.1371/journal.pone.0155694. PMID: 27196316; PMCID: PMC4873244.
Barnes CA, Markowska AL, Ingram DK, Kametani H, Spangler EL, Lemken VJ, Olton DS. Acetyl-1-carnitine. 2: Effects on learning and memory performance of aged rats in simple and complex mazes. Neurobiol Aging. 1990 Sep-Oct;11(5):499-506. doi: 10.1016/0197-4580(90)90110-l. PMID: 2234280.
